Water Soluble/fragmented carbon nanotubes

vasos

 

Exogenous nanostructured tubular materials are able to induce selectively the anisotropic diffusion of water molecules in the surrounding medium in a manner detectable by MRI methods. Homogeneous pi-pi stacking adducts multiwalled carbon nanotubes (MWNTs-Gd(III)DOTAPyrene derivatives) of relatively uniform distributions (around 170 nm) have been prepared, are highly water soluble and easily functionalized.

  • Negri,V., Cerpa,A., Lopez-Larrubia,P., Cerdan,S., Ballesteros,P. (2010) Nanotubular Paramagnetic Probes as contrast agents for Magnetic Resonance Imaging based in the Diffusion Tensor. Angewandte Chemie Int. Ed. (2010) 49(10):1813-5.
  • Cerpa, A., Köber,M., Calle,D., Negri, V., Gavira, .M., Hernanz, A., Cerdán, S., Ballesteros,P. (2013) Single Wall Carbon Nanotubes as anisotropic relaxation probes for magnetic resonance imaging. Med. Chem. Comm. 4: 90-110